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Abonner SemBioSys, Genetics Inc

SemBioSys, Genetics Inc

/C O R R E C T I O N -- SemBioSys Genetics Inc./

Calgary , Canada (ots/PRNewswire)

In the news release,
"SemBioSys Announces First Quarter Results" issued on 3  May 2007
11:00 GMT, by SemBioSys Genetics Inc. TSX:SBS over PR Newswire, we
are advised by a representative of the company that errors occurred
in the  headings of the financial tables. The comparative years were
transposed by  CNW in error.   Complete corrected copy follows:
  • SemBioSys Announces First Quarter Results
  • Canadian Biotechnology Company Achieves Insulin Milestones and
Strengthens Balance Sheet
SemBioSys Genetics Inc. (TSX: SBS), a biotechnology company
developing insulin and other metabolic and cardiovascular
protein-based pharmaceuticals and a series of non-pharmaceutical
products, today announced its operational and financial results for
the 2007 first quarter which ended on March 31, 2007.
     First Quarter Highlights
     -  Demonstrated the functional equivalence of the Company's proprietary
        safflower-produced insulin to U.S. pharma grade human insulin in
        animal models. The Company also announced in vitro and in vivo assay
        results that demonstrate the Company's safflower-produced insulin is
        chemically, structurally and physiologically indistinguishable from
        U.S. pharma grade human insulin.
     -  Confirmed that the Company is eligible to pursue a Section 505(b)(2)
        regulatory path for safflower-produced insulin after meeting with the
        U.S. Food and Drug Administration (FDA).
     -  Harvested over 300 acres of the Company's proprietary transgenic
        safflower-produced ImmunoSphere(TM) Feed Additive in Chile as part of
        its counter seasonal commercial scale-up in preparation for product
        launch later this year or early in 2008.
     -  Renegotiated the Company's docosahexaenoic acid (DHA) collaboration
        agreement with Martek Biosciences Corporation (Martek). Under the
        terms of the amended agreement, SemBioSys received a license fee of
        US$750,000 in January 2007 and was entitled to receive an additional
        license fee of up to US$250,000 upon delivery of seed and the
        achievement of expression of at least five percent of DHA in
        Arabidopsis prior to April 19th, 2007. Subsequent to the end of the
        quarter, the Company reported to Martek the existing proof-of-concept
        results from its DHA-rich safflower oil program. To date, SemBioSys
        has not achieved the five percent DHA accumulation threshold in
        Arabidopsis, although progress in this direction has been achieved.
        SemBioSys is, therefore, no longer eligible for the additional
        (US$250,000) license fee. However, SemBioSys is continuing to analyze
        the remaining DHA Arabidopsis lines from the development program to
        determine its ability to establish proof-of-concept. These results
        will be reported to Martek shortly.
     -  Completed an underwritten public offering, concurrent with a
        secondary offering, for aggregate gross proceeds of $24,150,000. The
        total gross proceeds to the Company from the treasury offering,
        including the over-allotment option, were $15,904,488. The secondary
        offering involved certain shareholders of the Company that sold
        2,748,504 previously issued common shares of the Company representing
        $8,245,512.
"With our two critical insulin announcements in the first quarter,
we continue to advance the development of our safflower-produced
insulin program toward the initiation of a Phase II clinical trial
which we expect to  commence in early 2008 with pharmacokinetics and
pharmacodynamics as the  primary endpoints," said Andrew Baum,
President and CEO of SemBioSys Genetics  Inc. "In parallel to our
insulin development, we are also advancing our Apo  AI program and
our non-pharmaceutical pipeline. Specifically, during the next  few
months we intend to actively pursue business development alternatives
to  maximize the value of the DermaSphere(R) Oleosome Technology to
the Company  and execute pond trials with our ImmunoSphere(TM) Shrimp
Feed Additive  product."
Financials
Total revenues for the three-month period ended March 31, 2007
were $542,788 compared with $100,086 for the corresponding period in
2006. Total revenues for the three-month period ended March 31, 2007
consisted of  $437,012 in license fees, compared with $nil during the
same period last year  and $105,776 in contract research compared
with $100,086 for the  corresponding period last year. The change in
license fee revenue relates  entirely to the partial recognition of
the upfront license fee payment  received from Martek as part of the
amended collaboration agreement which  included a US$750,000 license
fee payment that was received upon signing of  the contract in
January 2007.
Total expenditures for the three-month period ended March 31, 2007
were $3,943,408, compared with $2,748,954 for the corresponding
period last year.
Research and development expenses for the three-month period ended
March 31, 2007 were $1,905,422, compared with $1,107,526 for the
three-month period ended March 31, 2006. The difference is primarily
due to increased personnel and the related support costs in all areas
of research and development with an expanded focus on insulin. This
included an enhanced quality control and assurance program and
further development of a stronger preclinical and clinical team.
General and administrative expenses for the three-month period
ended March 31, 2007 were $1,023,711, compared with $972,260 for the
corresponding period last year.
Intellectual property costs for the three-month period ended March
31, 2007 were $528,249 compared with $263,037 for the three-month
period ended March 31, 2006. The difference is mainly attributable to
the timing of, and  an increase in, patent costs and as a result of
the final remaining  US$100,000 payment to re-acquire rights to the
DermaSphere(R) Oleosome  Technology from Lonza Inc., which became due
during the first quarter of  2007.
Business development costs for the three-month period ended March
31, 2007 were $148,005 compared with $184,805 for the corresponding
period last year.
Net loss for the three-month period ended March 31, 2007 was
$3,228,411 or ($0.17) per share, compared to a net loss of $2,504,339
or ($0.15) per share for the three-month period ended March 31, 2006.
As at March 31, 2007 the Company had cash and cash equivalents
totaling $28,805,937 compared to $16,328,459 at December 31, 2006.
Management believes the existing capital resources are adequate to
fund its current plans for research and development activities into
early 2009. Total long-term debt at March 31, 2007 was $1,877,377
compared to $2,084,103 at December 31, 2006.  The increase in cash
resulted from an underwritten public offering, including  the
exercise of the over-allotment option, of 5,301,496 common shares at
a  price of $3.00 per share, for total gross proceeds to SemBioSys of
$15,904,488.
As at March 31, 2007 the Company had 22,083,886 common shares
outstanding, 3,102,796 warrants, and 1,436,494 options.
Outlook
The Company has completed the major scientific milestones
necessary to proceed into first-in-man clinical trials of
safflower-produced insulin in early 2008. Additional insulin
milestone events expected in 2007 include:
-   Complete the scale-up and preclinical development of
         safflower-produced insulin
     -   Complete the technology transfer and production of clinical grade
         material for early stage human trials
     -   Initiate business development activities toward an insulin
         partnership
     -   Submit insulin IND to the FDA and prepare for Phase II trial
The Company is also advancing the development of its other
pharmaceutical and non-pharmaceutical products. The 2007 milestone
events  expected from these programs include:
-   Announce results of animal trials from Arabidopsis-produced Apo AI
     -   Achieve commercial levels of Apo AI expression in safflower
     -   Increase production capacity of personal care topical oilbody
         products and establish distribution channels for commercialization
     -   Initiate and complete pond trials for ImmunoSphere(TM)
     -   Complete processing of harvested ImmunoSphere(TM) product
     -   Initiate a new pharmaceutical product development program
Additional information about the Company, including the MD&A and
financial results may be found on SEDAR at www.sedar.com.
About SemBioSys Genetics Inc. (www.sembiosys.com)
Calgary, Alberta-based SemBioSys Genetics Inc. is a biotechnology
company developing insulin and other protein-based pharmaceuticals
for  metabolic and cardiovascular diseases. The Company's lead
candidate is  recombinant human insulin produced in the plant host
safflower, to serve the  rapidly expanding global diabetes market and
to supply insulin for inhalation  and other alternative insulin
delivery technologies. The Company's other  protein-based
pharmaceutical candidate is a cardiovascular drug called Apo  AI.
SemBioSys is also developing a series of non-pharmaceutical products
addressing animal and aquaculture health, nutritional oils and human
topical  markets.
This press release contains certain forward-looking statements,
including, without limitation, statements containing the words
"believe", "may", "plan", "will", "estimate", "continue",
"anticipate", "intend", "expect" and other similar expressions which
constitute "forward-looking information" within the meaning of
applicable Canadian securities laws. Forward-looking statements
reflect the Company's current expectation and assumptions, and are
subject to a number of risks and uncertainties that  could cause
actual results to differ materially from those anticipated. These
forward-looking statements involve risks and uncertainties including,
but not limited to, changing market conditions, the successful and
timely completion of clinical studies, the establishment of corporate
alliances, the impact of competitive products and pricing, new
product development, uncertainties related to the regulatory approval
process and other risks detailed from time-to-time in the Company's
ongoing filings with the Canadian securities regulatory authorities
which filings can be found at www.sedar.com. Given these risks and
uncertainties, readers are cautioned not to place undue reliance on
such forward-looking statements. The Company undertakes no obligation
to publicly update or revise any forward-looking statements either as
a result of new information, future events or otherwise, except as
required by applicable Canadian securities laws.
Financial results included below:
     SemBioSys Genetics Inc.
     Consolidated Balance Sheets
     (Unaudited)
     As at March 31, 2007 and December 31, 2006
     (expressed in Canadian dollars)
                                                    March 31,    December 31,
                                                      2007           2006
                                                 -------------  -------------
                                                       $              $
     Assets
     Current assets
     Cash and cash equivalents                     28,805,937     16,328,459
     Accounts receivable                              192,842        526,002
     Interest receivable                              113,145        504,551
     Prepaid expenses, deposits and other             394,271        405,459
                                                 -------------  -------------
                                                   29,506,195     17,764,471
     Property and equipment                         5,480,474      5,157,163
                                                 -------------  -------------
                                                   34,986,669     22,921,634
                                                 -------------  -------------
                                                 -------------  -------------
     Liabilities
     Current liabilities
     Accounts payable and accrued liabilities       1,700,006      1,356,018
     Repayable advances                                     -         85,640
     Short-term portion of long-term debt             730,750        746,658
                                                 -------------  -------------
                                                    2,430,756      2,188,316
     Deferred cost recoveries                         330,641         84,203
     Deferred revenue                                 437,012              -
     Long-term debt                                 1,146,627      1,337,445
                                                 -------------  -------------
                                                    4,345,036      3,609,964
                                                 -------------  -------------
     Shareholders' Equity
     Capital stock                                 62,681,360     48,302,036
     Warrants                                       6,274,716      6,274,716
     Contributed surplus                            5,654,454      5,475,404
     Deficit                                      (43,968,897)   (40,740,486)
                                                 -------------  -------------
                                                   30,641,633     19,311,670
                                                 -------------  -------------
                                                   34,986,669     22,921,634
                                                 -------------  -------------
     SemBioSys Genetics Inc.
     Consolidated Statements of Loss, Comprehensive Loss and Deficit
     (Unaudited)
     (expressed in Canadian dollars)                  Three month period
                                                        ended March 31,
                                                      2007           2006
                                                 -------------  -------------
                                                       $              $
     Revenue
     Licensing fees                                   437,012              -
     Contract research                                105,776        100,086
                                                 -------------  -------------
                                                      542,788        100,086
                                                 -------------  -------------
     Expenses
     Research and development                       1,905,442      1,107,526
     General and administration                     1,023,711        972,260
     Intellectual property costs                      528,249        263,037
     Business development                             148,005        184,805
     Stock-based compensation                         179,050         51,712
     Amortization                                     228,058        198,614
     Cost recoveries                                  (69,107)       (29,000)
                                                 -------------  -------------
                                                    3,943,408      2,748,954
                                                 -------------  -------------
     Loss before the undernoted                    (3,400,620)    (2,648,868)
                                                 -------------  -------------
     Interest income                                  212,233        220,080
     Interest expense                                 (57,973)       (48,848)
     Foreign exchange gain (loss)                      17,949        (26,703)
                                                 -------------  -------------
                                                      172,209        144,529
                                                 -------------  -------------
     Net loss and comprehensive loss for
      the period                                   (3,228,411)    (2,504,339)
     Deficit - Beginning of period                (40,740,486)   (26,613,400)
                                                 -------------  -------------
     Deficit - End of period                      (43,968,897)   (29,117,739)
                                                 -------------  -------------
                                                 -------------  -------------
     Loss per share - basic and diluted                 (0.17)         (0.15)
                                                 -------------  -------------
     SemBioSys Genetics Inc.
     Consolidated Statements of Cash Flows
     (Unaudited)
     (expressed in Canadian dollars)                  Three month period
                                                        ended March 31,
                                                      2007           2006
                                                 -------------  -------------
                                                       $              $
     Cash provided by (used in)
     Operating activities
     Net and comprehensive loss for the period     (3,228,411)    (2,504,339)
     Add items not affecting cash:
       Amortization                                   228,058        198,614
       Stock-based compensation                       179,050         51,712
       Unrealized foreign exchange (gain) loss        (21,010)        14,989
                                                 -------------  -------------
                                                   (2,842,313)    (2,239,024)
     Change in non-cash working capital and
      other balances related to operations          1,481,767        (96,966)
                                                 -------------  -------------
                                                   (1,360,546)    (2,335,990)
                                                 -------------  -------------
     Financing activities
     Issuance of capital stock                     15,904,488              -
     Share issue costs                             (1,356,539)             -
     Exercise of stock options                          4,500          5,102
     Repayment of long-term debt                     (183,969)      (143,845)
     Repayment of repayable advances                  (85,640)             -
                                                 -------------  -------------
                                                   14,282,840       (138,743)
                                                 -------------  -------------
     Investing activities
     Acquisition of property and equipment           (444,816)      (141,101)
                                                 -------------  -------------
                                                     (444,816)      (141,101)
                                                 -------------  -------------
     Increase (decrease) in cash and
      cash equivalents                             12,477,478     (2,615,834)
     Cash and cash equivalents - Beginning
      of period                                    16,328,459     28,513,095
                                                 -------------  -------------
     Cash and cash equivalents - End of period     28,805,937     25,897,261
                                                 -------------  -------------
                                                 -------------  -------------
     Supplemental Information
     Cash interest received                           603,639        201,784
     Cash interest paid                                51,422         44,995
     Non-cash transactions
       Capital items included in accounts payable     469,161         18,243
       Share issue costs included in accounts
        payable                                       168,939              -

Contact:

For further information: SemBioSys Genetics Inc., Mr. Andrew Baum,
President and Chief Executive Officer, Phone: +1-403-717-8767, Fax:
+1-403-250-3886, E-mail: bauma@sembiosys.com, Internet:
www.sembiosys.com; Investor Relations, Ross Marshall, The Equicom
Group Inc., Phone: +1-416-815-0700 (Ext.238), Fax: +1-416-815-0080,
E-mail: rmarshall@equicomgroup.com

Plus de actualités: SemBioSys, Genetics Inc
Plus de actualités: SemBioSys, Genetics Inc
  • 03.05.2007 – 13:05

    SemBioSys Announces First Quarter Results

    Calgary , Canada (ots/PRNewswire) - - Canadian Biotechnology Company Achieves Insulin Milestones and Strengthens Balance Sheet SemBioSys Genetics Inc. (TSX:SBS), a biotechnology company developing insulin and other metabolic and cardiovascular protein-based pharmaceuticals and a series of non-pharmaceutical products, today announced its operational and financial results for the 2007 first quarter which ...