off-market (euro adhoc) -

  Notification concerning transactions by persons discharging managerial
  responsibilities pursuant to section 15a of the WpHG, transmitted by euro
  adhoc with the aim of a Europe-wide distribution. The issuer is responsible
  for the content of this announcement.

24.04.2007

end of announcement                               euro adhoc 25.04.2007 18:01:21

Further inquiry note:

Andrea Weidner
Head of Public Relations
Tel.: +49 6027-4686-467
E-Mail: andrea.weidner@curasan.de

Branche: Biotechnology
ISIN: DE0005494538
WKN: 549453
Index: CDAX, Classic All Share, Prime All Share
Börsen: Frankfurter Wertpapierbörse / regulated dealing/prime
standard
Börse Berlin-Bremen / free trade
Hamburger Wertpapierbörse / free trade
Baden-Württembergische Wertpapierbörse / free trade
Börse Düsseldorf / free trade
Niedersächsische Börse zu Hannover / free trade
Bayerische Börse / free trade