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PEROS SYSTEMS TECHNOLOGIES INC

PerOs and the USDA's Agricultural Research Service Successfully Tested an Oral Vaccination Technology in Tilapia

ST- NICOLAS, Canada, November 16 (ots/PRNewswire)

Under a
cooperative research agreement signed in December of 2003 the
USDA-ARS and PerOs Systems Technologies Inc, conducted tests
combining PerOs' oral drug delivery technology, Oralject(TM), with
the USDA-ARS' vaccine developed against the streptococcal disease for
tilapia.
In a laboratory challenge test at the USDA, Agriculture Research
Service (ARS) Aquatic Animal Health Research Laboratory at Auburn,
Alabama. The USDA- ARS' streptococcus iniae vaccine was combined with
PerOs' Oralject(TM) and provided effective protection against the
disease. The protection degree is higher than any oral administration
tested in the past. Detailed results will be published in the next
few months.
The commercial availability of such oral vaccines will benefit the
aquaculture industry by reducing the impact of the disease and
eliminating the costs both direct and indirect associated with the
administering of injected vaccines, as well as reducing the use of
antibiotics in aquaculture. Streptococcal disease of fish is a
problem in farmed tilapia, hybrid striped bass, sea bass, sea bream,
yellowtail, and other fish species throughout the world. The total
value of loss in cultured fish due to streptococcal disease is
estimated at $US 150 million worldwide.
PerOs is proud to work in collaboration with the USDA-ARS to
provide an oral solution for the rapid and cost effective delivery of
the Streptococcus iniae vaccine to farmed fish.
Results "very exciting" says PerOs
"We have proved that it is possible to deliver orally the
Streptococcus iniae vaccine to tilapia. Moreover, this research has
demonstrated that the Oralject(TM) technology is able to deliver
macromolecules, contained in vaccines, to the bloodstream of the fish
in an effective quantity," stated Dr. Grant Vandenberg, Chief Science
Officer of PerOs Systems Technologies Inc.
About USDA-ARS:
The Agricultural Research Service (ARS) is the in-house research
center of the United States Department of Agriculture (USDA). ARS
conducts research to develop and transfer solutions to agriculture
problems of high national priority.
U.S. Department of Agriculture is a governmental organisation that
has the objective to help and improve the agriculture throughout the
United States. It has the responsibility to ensure the quality and
the safety of the product use in agriculture and introduce new
product on the market.
About PerOs:
PerOs Systems Technologies Inc. is a privately held biotechnology
company that has developed efficient non-encapsulation strategies to
provide oral administration of bioactive compounds (peptides,
vaccines, antibodies, etc.). The Company holds patents on a number of
these developments, and has commenced their commercialisation.
The company was set-up in Canada in early 2000 by Denis Bernier
and Dr. Grant Vandenberg after a revolutionary discovery that permits
oral delivery of therapeutic molecules including vaccines, peptides
and nutraceuticals. PerOs' patented technology, Oralject(TM), will
revolutionise drug delivery by providing a very low-cost and
effective large molecule delivery alternative to current drug
delivery systems, including injection. Oralject(TM) technology is the
first means of delivering large molecules in a cost-effective,
accurate, modulated, safe and efficient manner.

Contact:

For further information: Jean-Simon Venne, Vice President Business
Development, PerOs Systems Technologies Inc., +1-(514)-481-0349,
jsvenne@PerOsbio.com