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Merial Launches New H5N1 Avian Influenza Vaccine

Duluth, Georgia (ots/PRNewswire)

- Vaccine provides new hope for avian flu epidemic
Merial today announced the introduction of a new inactivated
vaccine, GALLIMUNE(R) Flu H5N9, developed and shown to be effective
specifically for use against the highly pathogenic avian influenza
virus H5N1 that has caused devastating economic losses in the poultry
industry in Asia, and which has been linked to the deaths of over 29
humans.
Once vaccinated by GALLIMUNE Flu H5N9, chickens can be readily
differentiated from infected birds through the use of the DIVA
(differentiating infected from vaccinated animals) serological
diagnostic test, which detects a non-pathogenic influenza strain
contained in the vaccine.
GALLIMUNE Flu H5N9, an inactivated vaccine, joins TROVAC(R) AIV H5
as Merial's second major introduction of avian influenza vaccines.
Recently conducted experiments with TROVAC AIV have shown the
efficacy of this fowlpox vector avian influenza vaccine against the
pathogenic Asian H5N1 virus. Tests conducted at government
laboratories in the United States and Australia demonstrated
significant levels of protection against viruses isolated in Korea
and Vietnam. The vaccine was also able to reduce or eliminate the
shedding of the virulent virus from the vaccinated chickens.
TROVAC AIV H5 is the only USDA licensed avian influenza vaccine
for administration to chickens at one day of age. More than one
billion doses of the TROVAC AIV H5 vaccine have been sold in Mexico
and Central America since 1998.
TROVAC data is also being evaluated by international agencies and
experts for inclusion in international guidelines for controlling and
preventing avian influenza outbreaks.
Merial is a world-leading, innovation-driven animal health
company, providing a comprehensive range of products to enhance the
health, well-being and performance of a wide range of animals. Merial
employs approximately 6,000 people and operates in more than 150
countries worldwide. Its 2004 sales were in excess of US$1.8 billion.
Merial Limited is a joint venture between Merck & Co., Inc. and
sanofi-aventis. For more information, please see www.merial.com
GALLIMUNE and TROVAC are registered trademarks
Web site: http://www.merial.com

Contact:

Steve Dickinson of Merial Global, +1-678-638-3682, or
Steve.dickinson@merial.com ; or Margaret May of Merial Europe,
+44-1279-77-4602, or Margaret.may@merial.com