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Digene

Early detection of cervical cancer: Wolfsburg breaks new ground

Dreieich/Wolfsburg (ots)

The city of Wolfsburg is home to
Volkswagen, the car makers. Its reputation to date has mainly been as
a motor of progress in the development of modern production methods
for the automotive industry. But Wolfsburg is now about to make a
name for itself as a European pioneer in implementing better
strategies for preventing cervical cancer. Klinikum der Stadt
Wolfsburg (a hospital), Deutsche BKK (an insurance provider) and
Gesundheitsverbund Wolfsburg (Wolfsburg Alliance for Health, an
organization whose members include most of Wolfsburg's gynecologists)
signed an agreement to achieve this aim. The overriding goal is to
significantly reduce the numbers of women who fall prey to cervical
cancer, which claims some 2,000 women's lives every year in Germany,
with 7,000 new cases diagnosed annually.
HPV test to play a greater role
A key element of the new agreement is routine integration of HPV
testing as part of cervical cancer screening in combination with the
conventional Pap smear. The HPV test identifies the true cause of
cervical cancer, i.e. human papilloma viruses (HPV). In the absence
of these sexually transmitted viruses, malignant tumors are extremely
rare.
"Many years of research and study data in more than 100,000 women
prove that adding HPV testing to the screening program enables early
identification of more cases of cervical cancer and its dangerous
precursors than conventional screening," says Professor Karl Ulrich
Petry, head of the Gynecology Department at Klinikum Wolfsburg
hospital. The Pap smear has long been the mainstay of cervical cancer
screening, but fails to identify some women at risk. "Preliminary
results from a large pan-European study published just a few months
ago provided further confirmation of the benefits of HPV testing,"
Petry went on to say. Timely detection of pre-cancerous cells
(dysplasia) is key. The disease is virtually 100% preventable if
detected in the early stages.
The Pap smear-HPV test combination presents another significant
advantage: If the results of both the Pap smear and HPV test are
normal, cervical cancer and its precursors can be virtually ruled
out. Women testing negative on both procedures don't have to worry
for the next couple of years.
All human papilloma virus testing will be performed with the
internationally accepted Hybrid Capture 2 (hc2) HPV DNA Test(r),
developed by Digene Corp., which can be used in any routine lab
setting.
"This announcement in Germany is an important milestone for
cervical cancer screening and prevention programs globally, and will
trigger the attention other countries in Europe with similar public
healthcare systems as a new standard of care," said Xavier Bosch, MD,
Chief of the Epidemiology and Cancer Registration Unit for the
Catalan Institute of Oncology in Spain. "Implementation of HPV DNA
testing for routine screening introduces on a large scale the
next-generation technology for cervical cancer screening, which has
proven to offer significant advantages for the early detection of
cervical cancer and its precursor conditions around the world."
European pioneer
The Wolfsburg model for cervical cancer prevention could serve as
an example for other insurers and countries. Professor Petry: "The
Wolfsburg model puts clinical research into practice on a daily basis
to the benefit of women and the healthcare system. Deutsche BKK (the
insurance provider) and the local gynecologists involved in the
project have reason to be proud of breaking new ground in European
cancer care through the increased use of the HPV test and other
modern evaluation standards such as colposcopy. If we succeed in
motivating all the women of Wolfsburg to undergo modern screening,
Wolfsburg might soon deserve to be called a 'cervical cancer-free'
city."
Internet: http://www.digene.de

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